Browsing by Author "Bousbia Brahim Aida"

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    Portulaca oleracea L. des zone arides: étude écologique,enquête ethno-pharmacologique et formulation galénique
    (2024) Bousbia Brahim Aida
    This research was conducted to study the valorization of Portulaca oleracea L. (purslane) from the Algerian Southeast Sahara region. The study involved ethnopharmacological, ecological, physiological, phytochemical, and therapeutic aspects, culminating in the development of a galenic (pharmaceutical) formulation using the plant's roots and aerial parts. The ethnopharmacological survey provided crucial information about the use of purslane in cuisine and traditional medicine, including its anti-inflammatory, dental, antiseptic, and anticarcinogenic properties. The ecological assessment showed high diversity and balanced distribution of purslane across the studied locations, with around 60% similarity between the biological communities. The physiological study revealed that purslane is rich in organic and mineral matter, particularly in the aerial parts. It has the ability to regulate moisture and adapt to dry conditions. The carbohydrate, lipid, protein, and crude fiber contents varied between the plant parts. The phytochemical analysis identified phenolic compounds like chlorogenic acid, naringin, gallic acid, caffeic acid, vanillin, and p-coumaric acid, with higher levels in the roots compared to the aerial parts. The antioxidant activity was higher in the aerial parts, while the root extracts exhibited stronger antibacterial properties. The galenic formulation study showed that creams made with purslane, using either vaseline or lanolin as a base, as well as the plant's mucilage, were more effective than the pharmaceutical reference creams used as positive controls. Statistical analysis indicated that the lanolin-based creams at different concentrations were the most effective, with an optimal healing rate achieved at a concentration of 9.6%. In summary, this comprehensive study explored the valorization of Portulaca oleracea L. from the Algerian Southeast Sahara, covering its ethnopharmacological, ecological, physiological, phytochemical, and therapeutic aspects, culminating in the development of an effective galenic formulation.