Journal Articles

Permanent URI for this collectionhttps://dspace.univ-soukahras.dz/handle/123456789/300

Browse

Filter results by year or month

Now showing 1 - 20 of 94

Quality Characteristics of Some Algerian Olive Oils with Antioxidant Activity
(0202-04-01) Boudjema, S; LACHRAF, A; Fella, L; TOUARFIA, M; HABERRA, S
Herein, the physicochemical properties of ten samples of olive oil from various Algerian regions (the acidity, peroxide, and saponi¦cation index, the speci¦c extinction coe¨cient (K232, K270), the content of chlorophyll, carotenoids, and total polyphenols), in addition to their antioxidant activity were investigated and were compared with three other control samples. The physicochemical characteristics of the tested olive oils proved oil quality varying from virgin to extra virgin olive oil of excellent nutritious and healthy quality for the consumer according to the commercial standards recommended by the International Olive Council (IOC). Moreover, the olive oil collected samples showed that the antioxidant activity of oil samples from south Algeria (Sahara) is higher than that of Northern Algeria, and the oils of Chemlal variety exhibited higher antioxidant activity than that of Segoise variety.
Toxicity and perturbation of the metabolite contents by a chitin synthesis inhibitor in the mosquito larvae of Culiseta longiareolata
(2011-01-01) Bouaziz, A; Boudjelida, H; Soltani, N
Novaluron is an IGR of the benzoyl urea family, acting as a chitin synthesis inhibitor. The activity of a commercial formulation of Novaluron (10% EC) was tested, at different concentrations, ranging between 0.2 and 1.6 µg/l, against third and fourth-instar larvae of Culiseta longiareolata. (Diptera: Culicidae). The technical material showed a high level of activity with mortality recorded for both treated and following stages and happened after incomplete development. The LC50 values were 0.51 and 0.91 µg/l active ingredient for third and fourth instar larvae; and LC90 values were 2.32 and 4.30 µg/l respectively. In other experiments the compound was applied at LC50 and LC90 against the fourth instars larvae and its effects investigated on biochemical composition of larval body. Metabolite analyzes showed that novaluron affected significantly the amount of carbohydrates, lipids and proteins of fourth instars larvae starting from the day three following treatment. The carbohydrate and lipid amounts increased significantly whereas those of proteins decreased as compared with control series. For the same treated series a significant decrease was also recorded in the body weight with a decrease in development time. In the presence of chitin synthesis inhibitors, the last step of the chitin biosynthesis pathway is inhibited and the precursor is not converted in to chitin. It may either act on the hormonal level in the haemolymph to announce the synthesis, degradation or the inhibition of the metabolites. Than carbohydrates, lipids, proteins are under endocrine control and the exposure of the larvae to this xenobiotic product can modify the synthesis of these metabolites. The data obtained were discussed according to the mode of action of this insect growth regulator and the metabolism of lipids carbohydrates and proteins.
La bio-indication de la pollution aquatique par les microalgues (Cas de l'Oued "Bounamoussa" et du Lac des" Oiseaux"
(2013-01-30) Necib, A; Rezig, H; Boughedir, L.
Continental aquatic environments are complex, fragile and governed by specific physico- chemical ecosystems laws. Microalgae that colonize living precariously and totally dependent. The most tolerant genera adapt to the input of an exogenous substance or a change in physico-chemical parameters. We used microalgae as biological indicators of water pollution in two sites: Bounamoussa's River and Lake of the Birds (W.Tarf). The method applied is the index of organic pollution recommended by Palmer (1969), which is to translate the level of contamination in water samples. The observation of morphological characteristics of collected microalgae allowed us to identify 20 genera. We recorded 10 genera in Bounamoussa's River: Microcystis, Euglena, Lepocinclis, Gomphonema, Melosira, Navicula, Synedra, Chlorella, Closterium and Scenedesmus. At the Lake of the Birds, we noted the existence of 17 genera: Aphanizomenon, Anabaena, Cylindrospermum, Merismopedia, Microcystis, Phormidium, Synechocystis, Phacus, Cyclotella, Gomphonema, Navicula, Synedra, Ankistrodesmus, Chlorella, Closterium, Pediastrum and Scenedesmus. The results show that the highest algal densities are recorded in the Lake of the Birds, followed by the Bounamoussa's River. According to the pollution index Palmer (1969), we found that there is little organic pollution (index = 9) at Bounamoussa's River. However, the contamination at the site of the Lake of the Birds by organic matter is considered average (index= 12). Keywords: Organic pollution -Microalgae - Bioindication -Pollution tolerant genera of algae -Palmer index (1969).
Hepatoprotective Role of Gallic Acid on Sodium Fluoride-Induced Liver Injury in Rats
(2014-11-30) Bouasla, A; Bouasla, I; Boumendjel, A; El Feki, A; Messarah, M.,
This study was undertaken to evaluate the protective effect of Gallic acid (GA) on oxidative damages in liver of rats intoxicated by sodium fluoride. Rats were randomly divided into three groups of six animals each: group (C): served as a control; group (NaF): treated for three weeks with sodium fluoride (100 ppm in drinking water) and group (NaF+GA) : treated daily and for three weeks also by both of NaF and GA (20mg/Kg orally). It was found that NaF induced liver damages as evidenced by the elevation of plasma amino transferases (ALT, AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH) activities associated with a decrease in total protein, albumin and bilirubin levels. Hepatotoxicity was objectified by the significant increase of malondialdehyde (MDA) level and a decrease of antioxidant enzyme activities such as catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx) and reduced glutathione (GSH) in liver of NaF treated rats. However, the co-administration of gallic acid caused an amelioration of the previous parameters. This study clearly showed that gallic acid has protective role against the oxidative damage in sodium fluoride intoxicated rats. Keywords: Gallic acid, Hepatotoxicity, Oxidative stress, Rat, Sodium fluoride
Aeropalynological Analysis of Casuarina Genus (Casuarinaceae) in the Region of Sidi Amar (Annaba, North-East Algeria
(2014-12-22) Asma, N; Larbi, B
L’allergie au pollen, ou pollinose, est une affection saisonnière liée à la présence de grains de pollen des espèces anémophiles en abondance dans l’air. Dans la région méditerranéenne, elle affecte plus de 10 %de la population Afin d’étudier la teneur pollinique du Genre Casuarina (Casuarina-ceae ) dans l’atmosphère et l’effet des paramètres météoro logiques sur la production pollinique de ce genre, une étude aéropalynol ogique quotidienne au cours d’une période de 7 mois (Août 2012 - février 2013) a été réalisée dans la région de Sidi Amar (Sud d’Annaba) en utilisant la méthode gravimétrique de Durham (1946). Nos résultats montrent que le pollen de Casuarina est présent dans l'air à partir du début septembre jusqu'à la 1ère semaine de février. Les premiers grains apparaissent le 07/09/2012. Un total de 1956 grains de pollen (GP) a été capturé durant la période d'étude. L’émission pollinique est élevée au cours de la première semaine du mois de novembre (337 GP), la 2ème semaine de septembre (202 GP) et la 2ème semaine de décembre (167 GP). Alors qu'elle est restée nulle durant deux semaines au mois d’octobre. A partir des résultats statistiques, nous avons constaté qu’il existe une faible corrélation positive entre la production pollinique et la température moyenne, négative avec les précipitations et fortement négative avec la vitesse du vent.
Outbreak of Serratia marcescens Coproducing ArmA and CTX-M-15 Mediated High Levels of Resistance to Aminoglycoside and Extended-Spectrum Beta-Lactamases, Algeria
(2015-02-14) Batah, R; Loucif, L; Olaitan, A.O.
Serratia marcescens is one of the most important pathogens responsible for nosocomial infections worldwide. Here, we have investigated the molecular support of antibiotic resistance and genetic relationships in a series of 54 S. marcescens clinical isolates collected from Eastern Algeria between December 2011 and July 2013. The 54 isolates were identified by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS). Antibiotic susceptibility testing was performed by disc diffusion and E-test methods. Antibiotic resistance genes were detected by polymerase chain reaction (PCR). The genetic transfer of antibiotic resistance was performed by conjugation using azide-resistant Escherichia coli J53 as the recipient strain, and plasmid analysis was done by PCR-based replicon typing. The relatedness of our isolates was determined by phylogenetic analysis based on partial sequences of four protein-encoding genes (gyrB, rpoB, infB, and atpD) and then compared to MALDI-TOF MS clustering. Thirty-five out of 54 isolates yielded an extended-spectrum b-lactamase (ESBL) phenotype and carried blaCTX–M-15 (n = 32), blaTEM-1 (n = 26), blaTEM-71 (n = 1), blaSHV-1a (n = 1), and blaPER-2 (n = 12). Among these isolates, we identified a cluster of 15 isolates from a urology unit that coharbored ESBL and the 16S rRNA methyltransferase armA. Conjugation was successful for five selected strains, demonstrating the transferability of a conjugative plasmid of incompatibility group incL/M type. Phylogenetic analysis along with MALDI-TOF clustering likely suggested an outbreak of such isolates in the urology unit. In this study, we report for the first time the co-occurrence of armA methyltransferase with ESBL in S. marcescens clinical isolates in Eastern Algeria.
Antibacterial Activity of Sulfonamide Derivatives against Clinical Strains of Bacteria
(2016-01-01) Bendjeddou, A; Abbaz, T; Khacha, N; Benahmed, M; Gouasmia,A; Villemin, D
This study was performed in order to evaluate antibacterial activity of some sulfonamides derivatives against four different clinical strains of bacteria namely, Proteus Mirabilis Pseudomonas Aeraginosa, Escherichia Coli and Staphylococcus Aureus. The zones of inhibition were performed with the disk diffusion method. Minimum inhibitory concentrations (MIC) of the compounds against the test microorganisms were determined by the dilution broth method. The result of the present study indicated that all the synthesized compounds exhibited a broad spectrum of activity against both gram-positive and gram-negative bacteria. Keywords: Sulfonamide; Antibacterial activity; Minimum inhibitory concentrations (MIC); disc diffusion technique
A combined DFT and experimental study of proline/β-cyclodextrin inclusion complex
(2016-01-25) Zaboub,A.; Madi,F.; Merdes,R.; Mohamedi,M.; Nouar,L.
The binding of the L-proline (Pro) amino acid with β-cyclodextrin (β-CD) was investigated theoretically by B3LYP/3-21G+ method and experimentally by UV–visible and FTIR techniques. Two modes of complexation were considered for studying such complex; in A complex the pyrrolidine ring of the guest was directed toward secondary hydroxyls of β-CD, while in B complex the pyrrolidine was directed toward primary one. Energetic analysis indicates that the formed complexes are stable and both host and guest were deformed after complexation. Electronic properties given by TD-DFT calculation and NBO analysis clearly demonstrate that a charge transfer was occurring between Pro and β-CD molecules.
Richness and Habitat Relationships of Forest Birds in the Zeen Oak Woodland (Forest of Boumezrane, Souk-Ahras), Northeastern Algeria
(2016-06-01) Menaa, M; Maazi, M.C; Telailia, S; Saheb, M; Boutabia, L; Chafrour, A; Houhamdi, M.
Boumezrane's forest is a significant center for biodiversity. Since last year the forest is facing destruction and degradation. Although the forest is recognized as an important area for avian diversity, it has never received ornithological attention. Many studies have been conducted on the relationship of birds with habitat features, however their associations are not completely understood. Hence we need information on the relationship between occurrence of birds and structural components of zeen oak habitats. We examined relative bird abundance by using the point count method and its relationship to environmental descriptors. A total of 68 visits of 39 bird species were recorded in the zeen oak stands. Avian species richness at each point count ranged between four and 14 species. The most dominant families in number of pairs are Paridae (121 pairs), Turdidae (115.5 pairs), Sylviidae (57.5 pairs), Picidae (55.5 pairs), and Fringillidae (43.5 pairs). They cater for more than 70% of the total abundance of the entire community. Using principal component analysis and canonical correspondence analysis methods, we determined that the size of trees with the height of shrub layer is an important criterion for differentiation of the avifauna of Boumezrane. The second criterion is the volume of tree stratum.
Geometric morphometric discrimination of the three African honeybee subspecies Apis mellifera intermissa, A. m. sahariensis and A. m. capensis (Hymenoptera, Apidae): Fore wing and hind wing landmark configurations
(2016-10-28) Barour,C; Baylac, M.
In this study, a landmark-based geometric morphometric analysis was carried out on three honeybee subspecies: Apis m. intermissa and A. m. sahariensis collected from Algeria, and, as a reference, A. m. capensis collected from South Africa. The aim of this study was to discriminate honeybee subspecies by patterns of shape variation of fore and hind wings. A total of 540 wings from 270 honeybee workers were analyzed. Our results revealed very high cross-validation classification rates (96.7% based on fore wing shape and 99.6% based on the combination of fore and hind wing forms respectively). Discrimination was better using shape and form (shape + centroid size) of the fore wings than of the hind wings. The wing form parameters were found to differ significantly in shape and centroid size among the three analyzed subspecies. Finally, it may be concluded that landmark-based geometric morphometrics could be a powerful tool to characterize the Algerian honey bees
Caracterisation Physico-Chimique Des Eaux Du Barrage Foum El-Khanga (Region De Souk-Ahras, Algerie)
(2017-01-01) Allalgua, A; Kaouachi, N; Boualeg, C; Ayari,A.
The objective of our work is to assess the quality of the dam Foum El-Khanga (east of Algéria) monthly during the year 2014. This study planned to make a physico-chemical characterization to highlight several parameters which come into play the determination of the quality of this water such as: temperature; pH; conductivity; turbidity; dissolved oxygen; title hydrotimetric; calcium; magnesium; title alcalimetric complet; nitrate; nitrite; ammoniacal nitrogen; sulfate; chloride; bicarbonate; phosphate; iron; biological oxygen demand (BOD) and chemical oxygen demands (COD). The results of physico-chemical analysis show that the water of this dam is characterized by a significant mineralization as indicated by high values of electrical conductivity and chloride. The results of principal component analysis (PCA) clearly showed a stronger relation between the hot season and temperature. However, the cold season was strongly correlated with mineralization and pollution parameters
Impact of an insect growth regulator on the development and the reproduction potency of mosquito
(2017-04-18) Bouaziz, A; Khedidja, A; Djeghader, N.E; Aïssaoui, L; Boudjelida, H.
Mosquitoes are medically and veterinary important vectors, responsible for the transmission of many human and animal diseases, such as malaria, yellow fever, dengue and West Nile Fever [1]. The management of disease vectors using conventional neurotoxic pesticides has failed because of the high reproductive ability, development of insecticide resistance of insect species and secondary effects on none target organisms and environment [2]. These reasons are leading the scientists to focus on the search of novel molecules without secondary effects. They proposed the insect growth regulators (I.G.Rs) as new pesticide alternative, that seem to be promising because of their specific mode of action on insects and their lower toxicity against non-target organisms; specially vertebrate, than conventional insecticides [3, 4, 5]. In the last decades, the I.G.Rs compounds have shown promising results in controlling insects of agricultural, medical and veterinary field [6, 7, 8]. Culex pipiens (Diptera, Culicidae) is the most widely distributed mosquito in the world and carries a number of diseases [9]. According to its large distribution, this represents the most interesting mosquito species in Algeria, particularly in urban areas and is generally controlled by conventional insecticides [10]. The disease spread depends directly on insect vector population and consequently, production of eggs by the insect could be a potential target for vector control. Therefore, the purpose of this study was to evaluate in laboratory, the effectiveness of an insect growth regulator, RH-0345, after treatment during the fourth instar larvae of the domestic mosquito Culex pipiens, and to provide better insights in the physiology of its mode of action.
Monitoring the Evolution of Pseudomonas aeruginosa Resistance against Routine Antibacterial Agents
(2017-05-17) Khacha, N; Bendjeddou, A; Abbaz, T; Chettebi, H
ABSTRACT Bacterial resistance to antibacterial is a major public health problem. To contribute to the monitoring of multidrug resistance of Pseudomonas aeruginosa, we have tested 356 strains. These were isolated from pathological products of outpatient or inpatient. These strains were identified by the highlighted specific pigments and gallery API 20NE then submitted to several sensitivity tests against antibacterial agents. The latter was evaluated by the diffusion method on agar medium. For chlorinated water which is the most widely used disinfectant worldwide, we sought the lethal concentrations by liquid-based diffusion method. The results demonstrated that among the amino glycoside only amikacin showed significant efficacy. Among beta-lactam, the imipenem and piperacillin are the most effective relative to other antibiotics tested. Among the antiseptics tested only hydrogen peroxide at 10 volumes demonstrated efficacy compared with iodine alcohol at 10% and surgical alcohol at 70°. Strains tested showed a tolerance at concentrations at least most important chlorinated water at 13 °. The latter has a static effect only up to 2%.
Anti-oxidant activity research of enzymatic biomarkers in protozoa (Paramecium sp.) under stress by manufactured nanoparticles
(2017-06-28) KHALDI, F; GRARA, N
The production of nanoparticles (NPs) is increasing rapidly for electronics, chemistry and biology applications. This interest is due to the very small size of NPs which provides them with many interesting properties such as rapid diffusion, high specific surface areas, reactivity in liquid or gas phase and a size close to bio-macromolecules. However, these extreme abilities might be a problem when considering a potentially uncontrolled exposure to the environment. For instance, nanoparticles might be highly mobile and rapidly transported in the environment or inside the body through a water or air pathway. Accordingly, the very fast development of these new synthetic nanomaterials raises questions about their impact on the environment and human health. We have studied the impact of manufactured nanoparticles (ZnO) on ciliated microorganisms (Paramecium sp.).Principles results show that the ZnO presence affects the paramecia growth. On the metabolic level, ZnO causes a disturbance in the rate of total protein and total carbohydrates. Regarding the biomarkers we identified disruption of glutathione (GSH)and catalase (CAT)activity. This study shows the importance of a model species for assessing the ZnO toxicity in laboratory tests. It is clear that ZnO is the oxidative stress source, which results in a stimulation of growth in Paramecium sp.,a disturbance in the total protein rate, carbohydrates, glutathione and catalase activity
Study of some biological parameters of Cyprinus carpio from Foum El-khanga Dam, Souk-Ahras, Algeria
(2017-07-04) Sahtout, F; Boualleg, C; Khelifi, N; Kaouachi,N; Boufekane,Bi; Brahmia, S; Mouaissia, W; Bensouilah, M.
Cyprinus carpio (Linnaeus, 1758) is a wide-world freshwater fish, and is among the top important aquaculture species of the world. Since there are no available data on the growth pattern of this species in Foum El-Khanga Dam Souk-Ahras, Algeria, this study was carried out to determine the condition factor, length-weight relationship, age and growth. A total of 347 specimens of C. carpio were collected from Foum El-Khanga Dam (Souk-Ahras, Algeria) by monthly sampling from March 2015 to February 2016. Significant differences were noticed between the mean length of females (33.44±0.38) and males (30.88±0.31). The age of the examined fishes ranged from 2- to 7-year-old, meanwhile the dominant age group was 3-year-old. The size frequency distributions and the growth parameters were analyzed according to ELEFAN method, using FISAT II software. The Von Bertalanffy growth parameters were found as asymptotic length, L∞ = 58.28 cm, asymptotic weight, W∞ = 2019.76 g, growth coefficient, K = 0.30 year-1, to = -0.47 year for both combined sexes, asymptotic length, L∞ = 48.83 cm, asymptotic weight, W∞ = 1148.56 g, growth coefficient, K = 0.49 year-1, to = -0.29 year for males, and asymptotic length, L∞ = 58.28 cm, asymptotic weight, W∞ = 2049.84 g, growth coefficient, K = 0.41 year-1, to = -0.34 year for females. Also, the results indicated that L∞ and W∞ values of females were higher than those of males. The growth performance index was estimated as Φ́́́́ = 3.008 for combined sexes, Φ́́́́ = 3.068 for males, and Φ́́́́ = 3.144 for females. The condition factor indicates good conditions of the C. carpio fish. Moreover, the length-weight relationship was estimated as W = 0.0181 × Lt2.859 (the coefficient of determination, R2 = 0.963) for both sexes. Statistical analyses showed that the b coefficient is significantly lower than 3 (negative allometry) for separated and combined sexes (t-test, p < 0.05), as well as the relationship between the length and the weight exhibited a high correlation.
Toxicité subChronique des Nanoparticule de ZnO chez Helix aspersa: Etude physiologique et Comportementale
(2017-10-10) Grara, N; Khaldi, F; Benamara, A; Zenir, Z; Abdemadjid, S; Bouloudenine, M
In this study we were interested in assessing the impact of ZnO based metal nanoparticles and their effects on body bioaccumulative bioindicator of environmental pollution and an indicator of health status Helix aspersa for the preservation of Human health. This is a sub chronic (28 days) by means of digestive absorption. The toxicity of ZnO is determined in the snail Helix aspersa using a bioassay conducted on laboratory animals exposed to increasing concentrations of ZnO (500 µg/g, 1000 µg/g, 5000 µg/g, 10000 µg/g, 15000 µg/g).Initial results show that the presence of metallic nanoparticles to ZnO growth caused an inhibition dosedependent in the shell diameter. The growth inhibition is also represented by a reduction dose - dependent on the weight of organs especially Soft (digestive gland and kidney), and reduced dose - dependent consumption rate and dry weight of the waste and compartmental disturbances were noted
Molecular characterization of carbapenemresistant Gram-negative bacilli clinical isolates in Algeria
(2018-01-01) Bourafa, N; Wafaa Chaalal; Bakour,S; Lalaoui, R; Boutefnouchet, N; Diene,S .D; Rolain, J-M.
Of the 68 GNB isolates, 13 (19%) showed reduced susceptibility to carbapenems, including, four Klebsiella pneumoniae, one Escherichia coli, six Acinetobacter baumannii, and two Pseudomonas aeruginosa. blaOXA-48 gene was detected in the five Enterobacteriaceae isolates, and blaOXA-23 was identified in all A. baumannii isolates. OprD mutations were revealed in the two P. aeruginosa isolates. A total of 11 out of the 13 carbapenem-resistant GNB were detected in inpatients, and the two remaining strains were isolated from outpatients. Molecular typing showed the presence of four sequence types (STs) among the OXA-48-producing K. pneumoniae isolates: ST101, ST147, ST163, and ST2017. ST533 was identified for the OXA-48 producing E. coli isolate. All of the A. baumannii and P. aeruginosa were assigned to the international clonal lineages ST2 and ST654, respectively
Mesure et contrôle des propriétés de quelques eaux souterraines de l’agglomération d’Ouled Driss, Algérie
(2018-04-03) KHALDI, F; SMATI, H; GRARA, N; SMATI, N; MAIZI, N; BOUKEHILI, K; GHEID, A.
Measuring and controlling groundwater properties in Ouled Driss, Algeria Ain Nechema, Ain Souda, Ain Ras Oued, and Ain Maa Bared are important sources of drinking water for the inhabitants of Ouled Driss (Souk Ahras Province, in northeastern Algeria). This article is a qualitative and quantitative study of the physicochemical and bacteriological properties of the water, based on Algerian potability standards and the regulations in force, intended to ensure consumers’ health and well-being. The results of the physicochemical analysis showed that these waters are mineralized with a high content of bicarbonate and calcium, compared with other ions. The results meet Algerian drinking water standards, except for their elevated levels of lead and sodium. The results of the bacteriological analysis showed the presence of several fecal contamination indicators, including total coliforms, fecal coliforms, and fecal streptococci. Several sources of pollution are the cause of this degradation in water quality: waste discharge from the urban area close to the springs and agricultural activities such as cattle breeding
Multi-biomarkers approach to the assessment of the southeastern Mediterranean Sea health status: Preliminary study on Stramonita haemastoma used as a bioindicator for metal contamination
(2018-05-25) Bouzahouane, H; Barour, C; Sleimi, N; Ouali, K.
The present study aimed to evaluate the responses of different biochemicals parameters associated with environmental pollution in the digestive gland of the gastropod mollusc Stramonita haemastoma. Physiochemical parameters and trace metal elements (Copper (Cu), Zinc (Zn), Chromium (Cr), Cadmium (Cd) and Lead (Pb)) were measured in seawater. Spatiotemporal variations in reduced glutathione (GSH), malondialdehyde (MDA) and metallothionein (Mt) as well as the specific activities of glutathione Stransferase (GST) and catalase (CAT) were evaluated in digestive gland of this species during a one-year period in 2013e2014. Samples collection was conducted at three sites. The results obtained showed seasonal fluctuations in GST and CAT activities and in the rate of Mt content. In addition, intersite variations in GSH, MDA, Mt and CAT were recorded in individuals. Also, trace metal elements concentrations determined by season in the digestive gland revealed spatial and temporal variations for Cu and Zn but they are below the limit of detection for Cd and Pb. The highest values were generally recorded in spring for Cu and in winter for Zn. In this first regional study using in S. haemastoma as a model, the biomarkers measured were seen to be inducible parameters to evaluate the health state of the organism and the overall quality of the study sites
Neurobehavioral symptoms and reproductive hormones from paint occupational exposure
(2018-05-30) Merghad, A; Cherif, A; Djabou Rabi, S.
Occupational exposure to paint compounds and the joint action of solvents-metals probably causes effects on neurobehavioral profiles, and reproductive hormones of male workers. We undertook this study to determine relationship between occupational exposure to paint compounds mixture, especially solvents and neurobehavioral perturbations, testosterone and prolactin production. Exposure was estimated in 64 workers from a paint manufacturing plants, North East Algeria. Two exposure groups were formed: and divided into 2 main groups; the control and the exposed groups; the latter was subdivided into three categories of working periods (>10, 10-20, > 20 years of solvent exposure). The Swedish Q16 questionnaire was given to workers, followed by serum testosterone and prolactin concentrations were measured with ELISA. Workers with long period exposure (10-20, > 20 years) showed a significant reduction in testosterone concentration, and a significant increase in prolactin concentration and The average Swedish Q16 questionnaire score in the exposed group (4.6±4.2) is also significantly higher than the non-exposed group (3.4±3.1) (p=0.001). Fertility markers assessed in workers with long solvent exposure were disturbed than in those with a short solvent exposure, long solvent exposure produced high frequency of neuropsychological symptoms